作者：王尉, 周晓晶, 乐胜锋, 杜宁, 林楠, 张经华

作者单位：北京市理化分析测试中心, 北京 100089

关键词：白藜芦醇;标准样品;定值;均匀性;稳定性

摘要：

依据GB/T 150002008标准样品工作导则,研制白藜芦醇标准样品.采用高速逆流色谱方法制备白藜芦醇样品,通过UV、IR、MS和NMR等方法对白藜芦醇样品进行结构鉴定,并进行均匀性、稳定性检验.采用8家实验室对制备的白藜芦醇样品进行联合定值,并对定值结果进行数据分析.白藜芦醇标准样品均匀性和稳定性良好,其定值结果为99.79%,置信度95% 的扩展不确定度为0.66%.所制备的白藜芦醇样品满足标准样品工作导则的要求,可用于有关白藜芦醇检测方法的校正和相关产品的质量控制.

Preparation of certified reference materials of resveratrol

WANG Wei, ZHOU Xiaojing, LE Shengfeng, DU Ning, LIN Nan, ZHANG Jinghua

Beijing Centre for Physical and Chemical Analysis, Beijing 100089, China

Abstract: Prepare certified resveratrol reference materials according to the Directives for the Work of Reference Materials GB/T 15000. The materials were separated by high-speed countercurrent chromatography. Its chemical structure was identified through ultraviolet, infrared radiation, mass spectra and nuclear magnetic resonance and its homogeneity and stability checked systematically. A cooperative certification was conducted with 8 laboratories and the certification data were analyzed. Results: the materials were homogeneous and stable with 99.79% of certification data and 0.66% of the expanded uncertainty for 95%-confidence coefficient. The materials prepared conform to the Directives for the Work of Reference Materials GB/T 15000, capable of correcting the test method of resveratrol and controlling the quality of relevant products.

Keywords: resveratrol;certified reference material;certification;homogeneity;stability

2015, 41(4): 39-42  收稿日期: 2014-8-22;收到修改稿日期: 2014-10-18

基金项目: 国家质检总局公益性行业科研发展专项(201210209)

作者简介: 王 尉(1984-),男,北京市人,助理研究员,硕士,研究方向为天然产物分离纯化.

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